A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

An archaeon reads the same codon in two different ways, overturning a doctrine that has stood for 60 years. Living organisms ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...