DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

In a study published in Science Translational Medicine, researchers at Cedars-Sinai report that an experimental drug called TY1 helped damaged hearts heal in laboratory animals. It did not thin blood ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

The first study to examine the extent of European ancestry biases in gene maps reveals tens of thousands of genetic ...