Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...

The biggest new healthcare product unveiled at CES this week was undoubtedly Life Technologies Corp.’s (NASDAQ:LIFE) new Ion Proton Sequencer, a bench-top machine that the company says will be able to ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

UC Santa Cruz has a long history of pioneering advances in genomics research. The first working draft of a human genome sequence was assembled on our campus in 2000, which has led to enormous leaps in ...

An international research team has generated the first truly complete sequence of a human Y chromosome, the final human chromosome to be fully sequenced. The new sequence, which fills in gaps across ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Whole-genome sequencing reads every DNA base. This shifts medicine from diagnosing disease based on symptoms to molecular ...