CRISPR-Cas technology has radically changed how transgenic models are created. Through CRISPR approaches, researchers have pioneered how to create complex animal models, including long cassette ...

CRISPR systems that rely on inactivated Cas enzymes—that is, dead Cas (dCas) enzymes—never looked more alive. They harness the targeting power associated with CRISPR—but not the double-strand cuts. As ...

Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are ...

Researchers have been able to manipulate large chunks of genetic code for almost 50 years. But it is only within the past decade that they have been able to do it with exquisite precision – adding, ...

For years, Yale researchers David Breslow and Mustafa Khokha have worked together with a similar challenge in their ...

Cancer and many other diseases are based on genetic defects. The body can often compensate for the defect of one gene; it is only the combination of several genetic errors that leads to the clinical ...

For decades, researchers have used Drosophila melanogaster as a model for developing and applying cutting-edge genetic approaches. These have helped scientists understand complex biological processes ...

OTTAWA, Nov. 19, 2020 (GLOBE NEWSWIRE) -- One of the most ground-breaking improvements in biology sector has its origins in the RNA-based defense system of bacteria, that encrypts CRISPR-associated ...