When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

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The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...

Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in ...

Every person starts as just one fertilized egg. By adulthood, that single cell has turned into roughly 37 trillion cells, many of which keep dividing to create the same amount of fresh human cells ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

A new study has revealed that certain locations of DNA are copied faster than others, which could also have an effect on mutation rate. Cell division is fundamental for life, allowing organisms to ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...