Base excision repair is a process that removes and replaces damaged or misincorporated bases in one strand of the DNA that may generate mutations if left unrepaired. The damaged base is modified and ...
Base excision repair (BER) is an evolutionarily conserved process for maintaining genomic integrity by eliminating several dozen damaged (oxidized or alkylated) or inappropriate bases that are ...
The most frequent DNA lesions (8-oxoguanine, thymine glycol, dihydrothymine, dU) (De Bont and van Larebeke, 2014) are removed from the genome by the BER (Kim and Wilson, 2012) (Figure 1). This repair ...
Damage to your DNA is unavoidable. Every day our cells are bombarded by gene-splitting UV radiation or chemical carcinogens. Regular water inside our bodies can cause DNA damage. DNA damage is as ...
This is a preview. Log in through your library . Abstract Base excision repair (BER) of DNA damage in irradiated THP1 human leukemic cells was stimulated by pretreating the cells with exogenous ...
There are over 150 human proteins that have been categorized as bona fide DNA Repair proteins. These fall into 14 general categories, including the classical DNA Repair pathways of Base Excision ...
In a paper to be published in the Nov. 25 issue of Proceedings of the National Academy of Sciences, the laboratory of cancer geneticist Alfonso Bellacosa, M.D., of Fox Chase Cancer Center reports new ...
The Nobel prize in chemistry has gone to research showing how DNA fixes the damage that can cause cancer and premature ageing. Tomas Lindahl of the Francis Crick Institute in Hertfordshire, UK, Paul ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback